Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery
نویسندگان
چکیده
منابع مشابه
Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury.
Gut injury and loss of normal intestinal barrier function are key elements in the paradigm of gut-origin systemic inflammatory response syndrome, acute lung injury, and multiple organ dysfunction syndrome (MODS). As hypoxia-inducible factor (HIF-1) is a critical determinant of the physiological and pathophysiological response to hypoxia and ischemia, we asked whether HIF-1 plays a proximal role...
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ژورنال
عنوان ژورنال: Annual Review of Physiology
سال: 2012
ISSN: 0066-4278,1545-1585
DOI: 10.1146/annurev-physiol-020911-153230